Vignettes

Developed for practical use: below you find a collection of practical examples and use-cases, the so-called rpact vignettes.

In addition to these public open access vignettes, our RPACT SLA customers have access to exclusive vignettes on special topics such as the analysis of multi-stage data with covariates from raw data.

# Title Sort ascending Category Endpoint Summary
11 Comparing Sample Size and Power Calculation Results for a Group Sequential Trial with a Survival Endpoint: rpact vs. gsDesign Planning Survival

This R Markdown document provides an example that illustrates how to compare sample size and power calculation results of the two different R packages rpact and gsDesign.

21 Analysis of a Multi-Arm Design with a Binary Endpoint using rpact Analysis Categorical

This R Markdown document shows how to analyse and interpret multi-arm designs for testing proportions with rpact.

Multi-arm
7 Analysis of a Group Sequential Trial with a Survival Endpoint using rpact Analysis Survival

This R Markdown document provides examples how to analyse a survival trial and provide inference throughout and at the end of the trial with rpact.

6 An Example to Illustrate Boundary Re-Calculations during the Trial with rpact Planning Survival

This R Markdown document provides an example for updating the group sequential boundaries when using an alpha-spending function approach based on observed information rates in rpact. Since version 3.1 of rpact, an additional option in the getAnalysisResults() function provides an easy way to perform an analysis with critical values that are calculated subsequently during the stages of the trial.

Events

Presentation for the U.S. Food and Drug Administration (FDA), March 3, 2022, 9:00am - 11:00am…

03
Mar -

Online Training Course for PPD, January 13, 2022.

13
Jan -

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