Vignettes

Developed for practical use: below you find a collection of practical examples and use-cases, the so-called rpact vignettes.

In addition to these public open access vignettes, our RPACT SLA customers have access to exclusive vignettes on special topics such as the analysis of multi-stage data with covariates from raw data.

# Title Sort descending Category Endpoint Summary
5 Simulation-Based Design of Group Sequential Trials with a Survival Endpoint with rpact Planning Survival

This R Markdown document describes how to simulate design characterics for survival design under complex settings (incl. non-proportional hazards) in rpact.

Power simulation
22 Step-by-Step rpact Tutorial Getting started Categorical, Continuous, Survival

The R package rpact has been developed to design sequential and adaptive experiments. Many of the functions of the R package are available in an online Shiny app. For more information about rpact, including a quick start guide and manual, visit the rpact website. This step by step vignette accompanies the manuscript “Group Sequential Designs: A Tutorial” by Lakens, Pahlke, & Wassmer (2021).

12 Supplementing and Enhancing rpact’s Graphical Capabilities with ggplot2 Planning Continuous

The aim of this R Markdown document is to give a brief description on how easy it is to supplement and enhance plots generated in rpact by use of the ggplot2 package and associated language.

Power simulation
13 Using the Inverse Normal Combination Test for Analysing a Trial with Continuous Endpoint and Potential Sample Size Re-Assessment with rpact Analysis Continuous

This R Markdown document provides an example for analysing trials with a continuous endpoint and sample size reassessment using rpact.

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