R Package crmPack

Open Source
R Package
Software
Clinical Trials
GxP
The comprehensive validated, open source, free-of-charge R software package for dose escalation trial design, simulation and analysis.

crmPack is a comprehensive open source, free-of-charge R software package for:

  • Dose escalation trial planning
  • Dose escalation trial design evaluation and simulation
  • Dose escalation trial data analysis

Functional Range

  • Dose escalation trial design, simulation and analysis
  • Binary, time-to-event, dual efficacy/safety, ordinal outcomes
  • Backfill cohorts
  • >15 different models
  • >14 different recommendation options
  • >19 different stopping rules
  • >9 cohort size rules
  • >9 increment rules
  • Reporting functionality (using knitr)

More high quality graphics produced by crmPack can be found in the gallery.

Installation

Install the latest CRAN release via

install.packages("crmPack")

Development version

To use a feature from the development version, you can install the development version of crmPack from GitHub.

# install.packages("pak")
pak::pak("openpharma/crmPack")

Documentation

The documentation is hosted at crmPack.org

Vignettes

The vignettes are hosted at crmPack.org/vignettes